Issues for consideration in the analysis of microarray data in behavioural studies

被引：4

作者：

Barr, GA

Gao, PH

机构：

[1] New York State Psychiat Inst & Hosp, Dept Dev Psychobiol, New York, NY 10032 USA

[2] Columbia Univ, Dept Psychiat, Med Ctr, New York, NY 10027 USA

[3] CUNY, Dept Psychol, Hunter Coll, New York, NY 10021 USA

[4] CUNY, Grad Sch, New York, NY 10021 USA

来源：

ADDICTION BIOLOGY | 2005年 / 10卷 / 01期

关键词：

D O I：

10.1080/13556210412331308930

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microarrays are one of several technologies that allow for measurement the expression of thousands of genes simultaneously. This technological advance provides a challenge for the analysis of these data. In this review we discuss these analytical issues from the initial quality control to normalization, differential expression, clustering and finally functional pathway analysis. Me focus on Affymetrix data but many of the issues are the same for other array platforms.

引用

页码：15 / 21

页数：7

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