How do RNA folding algorithms work?

被引：82

作者：

Eddy, SR

机构：

[1] Washington Univ, Sch Med, Howard Hughes Med Inst, St Louis, MO 63108 USA

[2] Washington Univ, Sch Med, Dept Genet, St Louis, MO 63108 USA

来源：

NATURE BIOTECHNOLOGY | 2004年 / 22卷 / 11期

关键词：

D O I：

10.1038/nbt1104-1457

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Programs such as MFOLD and ViennaRNA are widely used to predict RNA secondary structures. How do these algorithms work? Why can't they predict RNA pseudoknots? How accurate are they, and will they get better?

引用

页码：1457 / 1458

页数：2