Zirconium and hafnium cations rapidly cleave model phosphodiesters in acidic aqueous solutions

被引：34

作者：

Moss, RA ^{[1
]}

Zhang, J ^{[1
]}

Ragunathan, KG ^{[1
]}

机构：

[1] Rutgers State Univ, Dept Chem, New Brunswick, NJ 08903 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(98)00074-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aqueous solutions of 20-fold excess Zr4+ and Hf4+ at pH 3.5 (37 degrees C) hydrolyze phosphodiester substrates 1-3 very rapidly. The reactivity of Zr4+ (with rate constants up to 0.015 s(-1) for 2 at 1 mM Zr4+) exceeds that of most other transition metal cations. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1529 / 1532

页数：4

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