Occurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany

被引：193

作者：

Dumke, R. ^{[1
]}

von Baum, H. ^{[2
]}

Lueck, P. C. ^{[1
]}

Jacobs, E. ^{[1
]}

机构：

[1] Tech Univ Dresden, Med Fac Carl Gustav Carus, Inst Med Microbiol & Hyg, D-01307 Dresden, Germany

[2] Univ Ulm Klinikum, Dept Med Microbiol & Hyg, Ulm, Germany

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2010年 / 16卷 / 06期

关键词：

23S rRNA; community-acquired pneumonia; macrolide resistance; Mycoplasma pneumoniae; real-time PCR; COMMUNITY-ACQUIRED PNEUMONIA; REAL-TIME PCR; MOLECULAR ANALYSIS; IN-VITRO; SAMPLES; CHINA; GENE;

D O I：

10.1111/j.1469-0691.2009.02968.x

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

In a total of 167 respiratory tract specimens from adult outpatients with confirmed Mycoplasma pneumoniae pneumonia, sampled between 2003 and 2008, and a further 99 isolates obtained from patients between 1991 and 2009 in Germany, M. pneumoniae was tested for macrolide resistance. Using PCR, real-time PCR and sequencing of the 23S rRNA gene, 1.2% of M. pneumoniae in the respiratory tract samples and 3.0% of the isolates were found to be resistant. The results indicate a limited but not negligible importance of macrolide-resistant M. pneumoniae in the population investigated, which requires the monitoring of macrolide susceptibility of isolates or the testing of respiratory samples by molecular methods.

引用

页码：613 / 616

页数：4

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