New cytotoxic sterols from the soft coral Gersemia fruticosa

被引:26
作者
Koljak, R
Lopp, A
Pehk, T
Varvas, K
Müürisepp, AM
Järving, I
Samel, N
机构
[1] Estonian Acad Sci, Inst Chem, EE-0026 Tallinn, Estonia
[2] Inst Chem Phys & Biophys, EE-0026 Tallinn, Estonia
基金
以色列科学基金会; 俄罗斯科学基金会;
关键词
D O I
10.1016/S0040-4020(97)10268-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Six new polyoxygenated sterols 1-6 were isolated from the soft coral Gersemia fruticosa. The structures of these compounds were determined by MS. H-1- and C-13- 1D and 2D FT NMR spectroscopy. Compounds 1-6 showed a moderate cytotoxic activity against human erythroleukemia K-562 cells and other leukemia cell lines. (C) 1997 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:179 / 186
页数:8
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