A system for in-vivo cardiac optical mapping

被引：32

作者：

Dillon, SM ^{[1
]}

Kerner, TE ^{[1
]}

Hoffman, J ^{[1
]}

Menz, V ^{[1
]}

Li, KS ^{[1
]}

Michele, JJ ^{[1
]}

机构：

[1] Allegheny Univ Hlth Sci, Hahnemann Div, Div Cardiol, Philadelphia, PA 19102 USA

来源：

IEEE ENGINEERING IN MEDICINE AND BIOLOGY MAGAZINE | 1998年 / 17卷 / 01期

关键词：

D O I：

10.1109/51.646226

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

An optical mapping system has been developed which allows the in-vitro analysis of cardiac electrical activity. While optical recording using excised cardiac tissues has proven to be very useful for illuminating basic issues of impulse propagation, re-entrant excitation, defibrillation, and cardiac electrophysiologic development, these results must be carefully extrapolated to the physiological conditions encountered in the intact organism. The system uses of a fiber-optic mapping plaque which consists of a 16×16 array of fiber optic pickups embedded in a flexible substrate.

引用

页码：95 / 108

页数：14

共 90 条

[1] INTRACELLULAR-RECORDING OF INSITU VENTRICULAR CELLS DURING VENTRICULAR-FIBRILLATION [J].

AKIYAMA, T .

AMERICAN JOURNAL OF PHYSIOLOGY, 1981, 240 (04) :H465-H471

[2]

[Anonymous], 1985, Cardiac arrhythmias

[3]

BOVE R, 1996, CIRCULATION S, V98, P714

[4] EXCITATION AND DETECTION OF ACTION POTENTIAL-INDUCED FLUORESCENCE CHANGES THROUGH A SINGLE MONOMODE OPTICAL FIBER [J].

BOWMASTER, TA ;

DAVIS, CC ;

KRAUTHAMER, V .

BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1091 (01) :9-14

[5] CHANGES IN AXON FLUORESCENCE DURING ACTIVITY - MOLECULAR PROBES OF MEMBRANE-POTENTIAL [J].

COHEN, LB ;

SALZBERG, BM ;

DAVILA, HV ;

ROSS, WN ;

LANDOWNE, D ;

WAGGONER, AS ;

WANG, CH .

JOURNAL OF MEMBRANE BIOLOGY, 1974, 19 (1-2) :1-36

[6] OPTICAL MEASUREMENT OF MEMBRANE-POTENTIAL [J].

COHEN, LB ;

SALZBERG, BM .

REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY, 1978, 83 :35-88

[7]

COHEN LB, 1986, OPTICAL METHODS CELL, P71

[8] Functional and structural assessment of intercellular communication - Increased conduction velocity and enhanced connexin expression in dibutyryl cAMP-treated cultured cardiac myocytes [J].

Darrow, BJ ;

Fast, VG ;

Kleber, AG ;

Beyer, EC ;

Saffitz, JE .

CIRCULATION RESEARCH, 1996, 79 (02) :174-183

[9] RESPONSE OF RELATIVELY REFRACTORY CANINE MYOCARDIUM TO MONOPHASIC AND BIPHASIC SHOCKS [J].

DAUBERT, JP ;

FRAZIER, DW ;

WOLF, PD ;

FRANZ, MR ;

SMITH, WM ;

IDEKER, RE .

CIRCULATION, 1991, 84 (06) :2522-2538

[10] SUSTAINED VORTEX-LIKE WAVES IN NORMAL ISOLATED VENTRICULAR MUSCLE [J].

DAVIDENKO, JM ;

KENT, PF ;

CHIALVO, DR ;

MICHAELS, DC ;

JALIFE, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (22) :8785-8789

← 1 2 3 4 5 6 7 8 9 →