Variation of toxigenic Vibrio cholerae 01 in the aquatic environment of Bangladesh and its correlation with the clinical strains

被引：16

作者：

Islam, MS

Talukder, KA

Khan, NH

Mahmud, ZH

Rahman, MZ

Nair, GB

Siddique, AKM

Yunus, M

Sack, DA

Sack, RB

Huq, A

Colwell, RR

机构：

[1] ICDDR B, Environm Microbiol Lab, Div Sci Lab, Ctr Hlth & Populat Res, Dhaka 1000, Bangladesh

[2] Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Int Hlth, Baltimore, MD 21205 USA

[3] Univ Maryland, Inst Biotechnol, Ctr Marine Biotechnol, Baltimore, MD 21202 USA

[4] Univ Maryland, Detp Cell Biol & Mol Genet, College Pk, MD 20742 USA

来源：

MICROBIOLOGY AND IMMUNOLOGY | 2004年 / 48卷 / 10期

关键词：

Vibrio cholerae 01; toxigenic variation; aquatic environment;

D O I：

10.1111/j.1348-0421.2004.tb03604.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The diversity of toxigenic V. cholerae O1 in the aquatic environment of Bangladesh is not known. A total of 18 environmental and 18 clinical strains of toxigenic V. cholerae O1 were isolated simultaneously from four different geographical areas and tested for variation by the pulsed-field gel electrophoresis method. Environmental strains showed diversified profiles and one of the profiles was common to some environmental strains and most clinical strains. It appears that one clone has an advantage over others to cause disease. These findings suggest that the study of the molecular ecology of V. cholerae O1 in relation to its environmental reservoir is important in identifying virulent strains that cause disease.

引用

页码：773 / 777

页数：5

共 26 条

[1] MOLECULAR CHARACTERIZATION OF VIBRIO-CHOLERAE O1 STRAINS BY PULSED-FIELD GEL-ELECTROPHORESIS [J].