Leakage of K+ ions from Staphylococcus aureus in response to tea tree oil

被引:26
作者
Hada, T [1 ]
Inoue, Y [1 ]
Shiraishi, A [1 ]
Hamashima, H [1 ]
机构
[1] Showa Pharmaceut Univ, Dept Microbiol, Machida, Tokyo 1948543, Japan
关键词
cell membrane; K+-selective electrode; Staphylococcus aureus; tea tree oil;
D O I
10.1016/S0167-7012(02)00248-8
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The leakage of K+ ions from Staphylococcus aureus in response to tea tree oil (TTO) was investigated with an ion-selective electrode. The amount of leaked K+ ions and the rate of leakage of K+ ions induced by TTO were dependent on the concentration of TTO. Measurements of initial rates required less time than measurements of total amounts and provided an index of the interaction between TTO and the cell membrane. Thus, the initial rate of leakage might be a more useful measure of the antibacterial activity of TTO than the total amount. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:309 / 312
页数:4
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