Disease prevalence and the index of detectability: A survey of studies of lung cancer detection by chest radiography

被引:15
作者
Kundel, HL [1 ]
机构
[1] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
来源
MEDICAL IMAGING 2000: IMAGE PERCEPTION AND PERFORMANCE | 2000年 / 3981卷
关键词
lung cancer; ROC analysis; technology evaluation; observer performance;
D O I
10.1117/12.383100
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A survey of 12 studies of lung cancer detection with cancer prevalence ranging from 0.9 to 476 cancers per 1000 showed that the unit-slope index of detectability, d', decreased from a high value of 3.9 at low prevalence to 1.4 at high prevalence. A proposed explanation is that the readers are operating on an ROC curve with a slope that is less than unity approximating 0.6. On such a curve, a shift to more stringent criteria that occurs with decreasing prevalence in order to minimize false positives, would result in a increased unity-slope d'.
引用
收藏
页码:135 / 144
页数:10
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