Emergence of new influenza A viruses which carry an escape mutation of the HLA-B27-restricted CTL epitope of NP in Japan

被引：3

作者：

Kashiwagi, T

Hamada, N

Iwahashi, J

Hara, K

Ueda, T

Noguchi, H

Toyoda, T

机构：

[1] Kurume Univ, Sch Med, Dept Virol, Fukuoka 8300011, Japan

[2] Nagasaki Prefectural Inst Publ Hlth, Nagasaki 8528061, Japan

来源：

MICROBIOLOGY AND IMMUNOLOGY | 2000年 / 44卷 / 10期

关键词：

influenza virus; NP; CTL epitope; HLA-B27;

D O I：

10.1111/j.1348-0421.2000.tb02576.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Influenza A viruses (H3N2) isolated in 1998 in Nagasaki, Japan, carried a mutation (384R-->G) in one of the anchor amino acids of the HLA-B27-restricted cytotoxic T lymphocyte (CTL) epitope of NP (383-391), Phylogenetic analysis revealed that these viruses have been isolated only in Japan to date and belong to the unique lineages.

引用

收藏

页码：867 / 870

页数：4

相关论文

共 29 条

[1] BIOLOGICAL AND GENETIC EVOLUTION OF THE NUCLEOPROTEIN GENE OF HUMAN INFLUENZA-A VIRUSES [J].

ALTMULLER, A ;

FITCH, WM ;

SCHOLTISSEK, C .

JOURNAL OF GENERAL VIROLOGY, 1989, 70 :2111-2119

[2] Previous H1N1 influenza A viruses circulating in the Mongolian population [J].

Anchlan, D ;

Ludwig, S ;

Nymadawa, P ;

Mendsaikhan, J ;

Scholtissek, C .

ARCHIVES OF VIROLOGY, 1996, 141 (08) :1553-1569

[3]

BEKLEMISHEV AB, 1986, BIOORG KHIM+, V12, P369

[4]

BROWNESS P, 1993, EUR J IMMUNOL, V23, P1417

[5] NUCLEOTIDE-SEQUENCE ANALYSIS OF THE NUCLEOPROTEIN GENE OF AN AVIAN AND A HUMAN INFLUENZA-VIRUS STRAIN IDENTIFIES 2 CLASSES OF NUCLEOPROTEINS [J].

BUCKLERWHITE, AJ ;

MURPHY, BR .

VIROLOGY, 1986, 155 (02) :345-355

[6] IDENTIFICATION OF SEQUENCE CHANGES IN THE COLD-ADAPTED, LIVE ATTENUATED INFLUENZA VACCINE STRAIN, A/ANN-ARBOR/6/60 (H2N2) [J].

COX, NJ ;

KITAME, F ;

KENDAL, AP ;

MAASSAB, HF ;

NAEVE, C .

VIROLOGY, 1988, 167 (02) :554-567

[7] INFLUENZA-VIRUS NAKED RNA CAN BE EXPRESSED UPON TRANSFECTION INTO CELLS CO-EXPRESSING THE 3 SUBUNITS OF THE POLYMERASE AND THE NUCLEOPROTEIN FROM SIMIAN VIRUS-40 RECOMBINANT VIRUSES [J].

DELALUNA, S ;

MARTIN, J ;

PORTELA, A ;

ORTIN, J .

JOURNAL OF GENERAL VIROLOGY, 1993, 74 :535-539

[8]

FELSENSTEIN J, 1985, EVOLUTION, V39, P783, DOI 10.1111/j.1558-5646.1985.tb00420.x

[9] 2-SUBTYPES OF NUCLEOPROTEINS (NP) OF INFLUENZA-A VIRUSES [J].

GAMMELIN, M ;

MANDLER, J ;

SCHOLTISSEK, C .

VIROLOGY, 1989, 170 (01) :71-80

[10] MOLECULAR CLOCK OF VIRAL EVOLUTION, AND THE NEUTRAL THEORY [J].

GOJOBORI, T ;

MORIYAMA, EN ;

KIMURA, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (24) :10015-10018