Sex hormone changes in morbidly obese patients after vertical banded gastroplasty

被引：91

作者：

Bastounis, EA

Karayiannakis, AJ

Syrigos, K

Zbar, A

Makri, GG

Alexiou, D

机构：

[1] Univ Athens, Laikon Hosp, Dept Surg 1, Athens, Greece

[2] Univ Athens, Laikon Hosp, Dept Internal Med 1, Endocrinol Unit, Athens, Greece

[3] Royal Postgrad Med Sch, Dept Surg, London, England

来源：

EUROPEAN SURGICAL RESEARCH | 1998年 / 30卷 / 01期

关键词：

morbid obesity; vertical banded gastroplasty; sex hormones; sex-hormone-binding globulin;

D O I：

10.1159/000008556

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Serum sex hormone levels were measured preoperatively in 57 morbidly obese patients (19 men and 38 premenopausal women) and 12 months after vertical banded gastroplasty. In the male group, there was a significant decrease in estradiol and an increase in follicle-stimulating hormone (FSH), total testosterone and sex-hormone-binding globulin (SHBG). Among female patients, a significant decrease in estradiol, total and free testosterone and an increase in FSH and SHBG was found. Irregular menses present preoperatively in 5 women were corrected after successful weight loss. In conclusion, altered sex hormonal levels and gynecologic abnormalities associated with morbid obesity are corrected with adequate weight loss following vertical banded gastroplasty.

引用

收藏

页码：43 / 47

页数：5

相关论文

共 25 条

[1] The impact of obesity on hormonal parameters in hirsute and nonhirsute women [J].

Bernasconi, D ;

DelMonte, P ;

Meozzi, M ;

Randazzo, M ;

Marugo, A ;

Badaracco, B ;

Marugo, M .

METABOLISM-CLINICAL AND EXPERIMENTAL, 1996, 45 (01) :72-75

[2] FAT TISSUE - A STEROID RESERVOIR AND SITE OF STEROID-METABOLISM [J].

DESLYPERE, JP ;

VERDONCK, L ;

VERMEULEN, A .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1985, 61 (03) :564-570

[3] CLINICAL ASSESSMENT OF BODY HAIR GROWTH IN WOMEN [J].

FERRIMAN, D ;

GALLWEY, JD .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1961, 21 (11) :1440-+

[4] LOW SERUM TESTOSTERONE AND SEX-HORMONE-BINDING-GLOBULIN IN MASSIVELY OBESE MEN [J].

GLASS, AR ;

SWERDLOFF, RS ;

BRAY, GA ;

DAHMS, WT ;

ATKINSON, RL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1977, 45 (06) :1211-1219

[5] SEX STEROID, GONADOTROPIN, CORTISOL, AND PROLACTIN LEVELS IN HEALTHY, MASSIVELY OBESE WOMEN - CORRELATION WITH ABDOMINAL FAT-CELL SIZE AND EFFECT OF WEIGHT-REDUCTION [J].

GRENMAN, S ;

RONNEMAA, T ;

IRJALA, K ;

KAIHOLA, HL ;

GRONROOS, M .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 63 (06) :1257-1261

[6] IMPROVEMENT IN ENDOCRINE AND OVARIAN-FUNCTION DURING DIETARY-TREATMENT OF OBESE WOMEN WITH POLYCYSTIC-OVARY-SYNDROME [J].

KIDDY, DS ;

HAMILTONFAIRLEY, D ;

BUSH, A ;

SHORT, F ;

ANYAOKU, V ;

REED, MJ ;

FRANKS, S .

CLINICAL ENDOCRINOLOGY, 1992, 36 (01) :105-111

[7] ANDROGEN-ESTROGEN METABOLISM IN WOMEN WITH UPPER BODY VERSUS LOWER BODY OBESITY [J].

KIRSCHNER, MA ;

SAMOJLIK, E ;

DREJKA, M ;

SZMAL, E ;

SCHNEIDER, G ;

ERTEL, N .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1990, 70 (02) :473-479

[8] MAINTENANCE OF NORMAL CIRCULATING LEVELS OF DELTA-4-ANDROSTENEDIONE AND DEHYDROEPIANDROSTERONE IN SIMPLE OBESITY DESPITE INCREASED METABOLIC-CLEARANCE RATES - EVIDENCE FOR A SERVO-CONTROL MECHANISM [J].

KURTZ, BR ;

GIVENS, JR ;

KOMINDR, S ;

STEVENS, MD ;

KARAS, JG ;

BITTLE, JB ;

JUDGE, D ;

KITABCHI, AE .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 64 (06) :1261-1267

[9] VISCERAL FAT ACCUMULATION IN RELATION TO SEX-HORMONES IN OBESE MEN AND WOMEN UNDERGOING WEIGHT-LOSS THERAPY [J].

LEENEN, R ;

VANDERKOOY, K ;

SEIDELL, JC ;

DEURENBERG, P ;

KOPPESCHAAR, HPF .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1994, 78 (06) :1515-1520

[10]

MASON EE, 1982, ARCH SURG-CHICAGO, V117, P701