Habitual Sleep Duration and Insomnia and the Risk of Cardiovascular Events and All-cause Death: Report from a Community-Based Cohort

被引:286
作者
Chien, Kuo-Liong [1 ,4 ]
Chen, Pei-Chung [2 ]
Hsu, Hsiu-Ching [1 ]
Su, Ta-Chen [1 ]
Sung, Fung-Chang [2 ]
Chen, Ming-Fong [1 ]
Lee, Yuan-Teh [1 ,3 ]
机构
[1] Natl Taiwan Univ Hosp, Dept Internal Med, Taipei 100, Taiwan
[2] China Med Univ, Coll Publ Hlth, Inst Environm Hlth, Taichung, Taiwan
[3] China Med Univ Hosp, Inst Clin Med Sci, Taichung, Taiwan
[4] Natl Taiwan Univ, Coll Publ Hlth, Inst Prevent Med, Taipei 10764, Taiwan
关键词
Sleep; cohort study; cardiovascular disease; CORONARY-HEART-DISEASE; OPERATING CHARACTERISTIC CURVES; WEIGHT-GAIN; FOLLOW-UP; MORTALITY; POPULATION; STROKE; ASSOCIATION; COMPLAINTS; ADULTS;
D O I
10.1093/sleep/33.2.177
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Study Objectives: To investigate the relationship between sleep duration and insomnia severity and the risk of all-cause death and cardiovascular disease (CVD) events Design: Prospective cohort study Setting: Community-based Participants: A total of 3,430 adults aged 35 years or older Intervention: None Measurements and Results: During a median 15.9 year (interquartile range, 13.1 to 16.9) follow-up period, 420 cases developed cardiovascular disease and 901 cases died. A U-shape association between sleep duration and all-cause death was found: the age and gender-adjusted relative risks (95% confidence interval [CI]) of all-cause death (with 7 h of daily sleep being considered for the reference group) for individuals reporting <= 5 h, 6 h, 8 h, and >= 9 h were 1.15 (0.91-1.45), 1.02 (0.85-1.25), 1.05 (0.88-1.27), and 1.43 (1.16-1.75); P for trend, 0.019. However, the relationship between sleep duration and risk of CVD were linear. The multivariate-adjusted relative risk (95% CI) for all-cause death (using individuals without insomnia) were 1.02 (0.86-1.20) for occasional insomnia, 1.15 (0.92-1.42) for frequent insomnia, and 1.70 (1.16-2.49) for nearly everyday insomnia (P for trend, 0.028). The multivariate adjusted relative risk (95% CI) was 2.53 (1.71-3.76) for all-cause death and 2.07 (1.11-3.85) for CVD rate in participants sleeping >= 9 h and for those with frequent insomnia. Conclusions: Sleep duration and insomnia severity were associated with all-cause death and CVD events among ethnic Chinese in Taiwan. Our data indicate that an optimal sleep duration (7-8 h) predicted fewer deaths.
引用
收藏
页码:177 / 184
页数:8
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