Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs

被引：44

作者：

Dapat, Clyde ^{[1
]}

Suzuki, Yasushi

Saito, Reiko ^{[2
]}

Kyaw, Yadanar ^{[4
]}

Myint, Yi Yi ^{[6
]}

Lin, Nay ^{[6
]}

Oo, Htun Naing ^{[6
]}

Oo, Khin Yi ^{[5
]}

Win, Ne ^{[5
]}

Naito, Makoto

Hasegawa, Go

Dapat, Isolde C.

Zaraket, Hassan

Baranovich, Tatiana

Nishikawa, Makoto ^{[3
]}

Saito, Takehiko

Suzuki, Hiroshi

机构：

[1] Niigata Univ, Dept Publ Hlth, Grad Sch Med & Dent Sci, Niigata 9518510, Japan

[2] Natl Inst Anim Hlth, Tsukuba, Ibaraki 305, Japan

[3] Niigata Prefectural Inst Publ Hlth & Environm Sci, Niigata 9502144, Japan

[4] Sanpya Hosp, Yangon, Myanmar

[5] Natl Hlth Lab, Yangon, Myanmar

[6] Cent Myanmar Dept Med Res, Nay Pyi Taw, Myanmar

来源：

EMERGING INFECTIOUS DISEASES | 2010年 / 16卷 / 03期

关键词：

B VIRUSES; RESISTANCE; OSELTAMIVIR; ZANAMIVIR;

D O I：

10.3201/eid1603.091321

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 2007 and 2008 in Myanmar, we detected influenza viruses A (H3N2) that exhibited reduced sensitivity to both zanamivir and amantadine. These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2.

引用

页码：493 / 496

页数：4

共 13 条

[1] Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005 [J].

Barr, I. G. ;

Hurt, A. C. ;

Iannello, P. ;

Tomasov, C. ;

Deed, N. ;

Komadina, N. .

ANTIVIRAL RESEARCH, 2007, 73 (02) :112-117

[2] Epidemiology of Human Influenza A and B Viruses in Myanmar from 2005 to 2007 [J].

Dapat, Clyde ;

Saito, Reiko ;

Kyaw, Yadanar ;

Naito, Makoto ;

Hasegawa, Go ;

Suzuki, Yasushi ;

Dapat, Isolde C. ;

Zaraket, Hassan ;

Cho, Tin Maung ;

Li, Danjuan ;

Oguma, Taeko ;

Baranovich, Tatiana ;

Suzuki, Hiroshi .

INTERVIROLOGY, 2009, 52 (06) :310-320

[3] Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus [J].

Gubareva, LV ;

Matrosovich, MN ;

Brenner, MK ;

Bethell, RC ;

Webster, RG .

JOURNAL OF INFECTIOUS DISEASES, 1998, 178 (05) :1257-1262

[4] Oseltamivir-Resistant Influenza Viruses A (H1N1), Norway, 2007-08 [J].

Hauge, Siri H. ;

Dudman, Susanne ;

Borgen, Katrine ;

Lackenby, Angie ;

Hungnes, Olav .

EMERGING INFECTIOUS DISEASES, 2009, 15 (02) :155-162

[5] Susceptibility of human influenza viruses from Australasia and South East Asia to the neuraminidase inhibitors zanamivir and oseltamivir [J].

Hurt, AC ;

Barr, IG ;

Hartel, G ;

Hampson, AW .

ANTIVIRAL RESEARCH, 2004, 62 (01) :37-45

[6] Zanamivir-Resistant Influenza Viruses with a Novel Neuraminidase Mutation [J].

Hurt, Aeron C. ;

Holien, Jessica K. ;

Parker, Michael ;

Kelso, Anne ;

Barr, Ian G. .

JOURNAL OF VIROLOGY, 2009, 83 (20) :10366-10373

[7] Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa [J].

Hurt, Aeron C. ;

Ernest, Joanne ;

Deng, Yi-Mo ;

Iannello, Pina ;

Besselaar, Terry G. ;

Birch, Chris ;

Buchy, Philippe ;

Chittaganpitch, Malinee ;

Chiu, Shu-Chun ;

Dwyer, Dominic ;

Guigon, Aurelie ;

Harrower, Bruce ;

Kei, Ip Peng ;

Kok, Tuckweng ;

Lin, Cui ;

McPhie, Ken ;

Mohd, Apandi ;

Olveda, Remigio ;

Panayotou, Tony ;

Rawlinson, William ;

Scott, Lesley ;

Smith, David ;

D'Souza, Holly ;

Komadina, Naomi ;

Shaw, Robert ;

Kelso, Anne ;

Barr, Ian G. .

ANTIVIRAL RESEARCH, 2009, 83 (01) :90-93

[8] Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir [J].

McKimm-Breschkin, J ;

Trivedi, T ;

Hampson, A ;

Hay, A ;

Klimov, A ;

Tashiro, M ;

Hayden, F ;

Zambon, A .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (07) :2264-2272

[9]

OKOMOADHIAMBO M, 2009, ANTIVIRAL RES 1113

[10] Amantadine-resistant influenza A (H3N2) virus in Japan, 2005-2006 [J].

Saito, Reiko ;

Li, Danjuan ;

Suzuki, Hiroshi .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (03) :312-313

← 1 2 →