Stereoselective synthesis of the C-linked analogue of β-D-galactopyranosyl-L-serine

被引：45

作者：

Dondoni, A ^{[1
]}

Marra, A ^{[1
]}

Massi, A ^{[1
]}

机构：

[1] Univ Ferrara, Dipartimento Chim, Chim Organ Lab, I-44100 Ferrara, Italy

来源：

TETRAHEDRON | 1998年 / 54卷 / 12期

关键词：

D O I：

10.1016/S0040-4020(98)83019-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The coupling of the D-serinal derivative 7 with the D-galactopyranosylmethylene phosphorane generated from the phosphonium salt 6 and reduction of the resulting alkene led to the C-glycosylated amino alcohol 9 that in turn was oxidized to the title amino acid in 44% overall yield. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2827 / 2832

页数：6

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