New cytotoxic sesquiterpenes from the gorgonian Isis hippuris

被引:47
作者
Sheu, JH [1 ]
Hung, KC [1 ]
Wang, GH [1 ]
Duh, CY [1 ]
机构
[1] Natl Sun Yat Sen Univ, Dept Marine Resources, Kaohsiung 80424, Taiwan
来源
JOURNAL OF NATURAL PRODUCTS | 2000年 / 63卷 / 12期
关键词
D O I
10.1021/np000271n
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Five new suberosane sesquiterpenes, suberosenol A (1), suberosenol B (2), suberosanone (3), suberosenol A acetate (4), and suberosenol B acetate (5), along with the known sesquiterpene subergorgic acid (6), have been isolated from the gorgonian Isis hippuris. The structures of these metabolites were established by spectroscopic and chemical methods. Metabolites 1 and 3-5 were found to exhibit potent cytotoxicity toward P-388, A549, and HT-29 cancer cell lines.
引用
收藏
页码:1603 / 1607
页数:5
相关论文
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