T cells doing it for themselves:: TGF-β regulation of Th1 and Th17 cells

被引：33

作者：

McGeachy, Mandy J. ^{[1
]}

Cua, Daniel J. ^{[1
]}

机构：

[1] Schering Plough Biopharma, Palo Alto, CA 94304 USA

来源：

IMMUNITY | 2007年 / 26卷 / 05期

关键词：

D O I：

10.1016/j.immuni.2007.05.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The source of TGF-beta, which regulates inflammation in various disease settings, is unclear. In this issue of Immunity, Li et al. (2007) find that not only does T cell-produced TGF-beta regulate Th1-cell-mediated inflammation, but it is also required for the generation of Th17 cells in vivo.

引用

页码：547 / 549

页数：3

共 10 条

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