γ-Frequency fluctuations of the membrane potential and response selectivity in visual cortical neurons

被引:37
作者
Volgushev, M
Pernberg, J
Eysel, UT
机构
[1] Ruhr Univ Bochum, Dept Neurophysiol, D-44780 Bochum, Germany
[2] Russian Acad Sci, Inst Higher Nervous Act & Neurophysiol, Moscow 117865, Russia
关键词
cat; gamma oscillations; intracellular recording; response selectivity; V1; visual cortex;
D O I
10.1046/j.1460-9568.2003.02609.x
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Fluctuations at frequencies of 25-70 Hz is an inherent property of cortical activity. These rapid, gamma-range fluctuations are apparent in the local field potentials, in spiking of cells and cell groups, and in the membrane potential of neurons. To investigate stimulus dependence of the gamma-frequency fluctuations of the membrane potential, we have recorded intracellularly responses of cells in cat visual cortex to presentation of moving gratings. We found gamma-range fluctuations of the membrane potential in both simple and complex cells. The strength of the gamma-frequency fluctuations correlated with the stimulus optimality. Furthermore, the amplitude of the gamma-frequency fluctuations correlated with the phase of stimulus-imposed slow changes of the membrane potential. The combination of these features makes cortical neurons capable of encoding the slow changes in the visual world in a kind of amplitude modulation of the high frequency fluctuations. This assures reliable transformation of the membrane potential changes into spike responses without compromising the temporal resolution of visual information encoding in the low frequency range.
引用
收藏
页码:1768 / 1776
页数:9
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