Emergence of fluconazole-resistant sterol 14-demethylase P450 (CYP51) in Candida albicans is a model demonstrating the diversification mechanism of P450

被引：13

作者：

Aoyama, Y

Kudo, M

Asai, K

Okonogi, K

Horiuchi, T

Gotoh, O

Yoshida, Y

机构：

[1] Mukogawa Womens Univ, Sch Pharmaceut Sci, Nishinomiya, Hyogo 6638179, Japan

[2] Soka Univ, Fac Engn, Dept Bioengn, Tokyo 1928577, Japan

[3] Mukogawa Womens Univ, Interdisciplinary Res Inst Biosci, Nishinomiya, Hyogo 6638179, Japan

[4] Takeda Chem Ind Ltd, Div Pharmaceut Res, Osaka 5328686, Japan

[5] Saitama Canc Ctr, Res Inst, Ina, Saitama 3620806, Japan

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 2000年 / 379卷 / 01期

关键词：

D O I：

10.1006/abbi.2000.1852

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：170 / 171

页数：2

共 5 条

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[4] Contribution of mutations in the cytochrome P450 14α-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans [J].

Marichal, P ;

Koymans, L ;

Willemsens, S ;

Bellens, D ;

Verhasselt, P ;

Luyten, W ;

Borgers, M ;

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Vanden Bossche, H .

MICROBIOLOGY-SGM, 1999, 145 :2701-2713

[5]

Yoshida Y, 1997, J BIOCHEM-TOKYO, V122, P1122

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