DNA-based barcodes, nanoparticles, and nanostructures for the ultrasensitive detection and quantification fo proteins

被引：54

作者：

Brakmann, S ^{[1
]}

机构：

[1] Univ Leipzig, Inst Biol 2, D-04103 Leipzig, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 43期

关键词：

antibodies; antigens; immunoassays; proteins;

D O I：

10.1002/anie.200461112

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Beyond the shadow of a doubt: Detecting antigens, antibodies, pathogens, tumor markers, and potential therapeutics on the femto- to attomolar concentration level is still challenging. Nanostructured materials and the innovative combination of immunoassays with (real-time) PCR and magnetic separation techniques hold promise for the field of ultrasensitive protein analytics.

引用

页码：5730 / 5734

页数：5

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