Substantially elevated levels of atorvastatin and metabolites in cyclosporine-treated renal transplant recipients

被引:49
作者
Hermann, M [1 ]
Åsberg, A
Christensen, H
Holdaas, H
Hartmann, A
Reubsaet, JLE
机构
[1] Univ Oslo, Sch Pharm, Dept Pharmacol, Oslo, Norway
[2] Natl Hosp, Dept Med, Lab Renal Physiol, Oslo, Norway
[3] Univ Oslo, Sch Pharm, Dept Pharmaceut Anal, Oslo, Norway
关键词
D O I
10.1016/j.clpt.2004.07.008
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:388 / 391
页数:4
相关论文
共 8 条
  • [1] Åsberg A, 2003, DRUGS, V63, P367
  • [2] Bilateral pharmacokinetic interaction between cyclosporine A and atorvastatin in renal transplant recipients
    Åsberg, A
    Hartmann, A
    Fjeldså, E
    Bergan, S
    Holdaas, H
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2001, 1 (04) : 382 - 386
  • [3] Billeclke S, 2000, DRUG METAB DISPOS, V28, P1335
  • [4] Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression
    Hedman, M
    Neuvonen, PJ
    Neuvonen, M
    Holmberg, C
    Antikainen, M
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2004, 75 (01) : 101 - 109
  • [5] A novel human hepatic organic anion transporting polypeptide (OATP2) - Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
    Hsiang, BN
    Zhu, YJ
    Wang, ZQ
    Wu, YL
    Sasseville, V
    Yang, WP
    Kirchgessner, TG
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (52) : 37161 - 37168
  • [6] Glucuronidation of statins in animals and humans: A novel mechanism of statin lactonization
    Prueksaritanont, T
    Subramanian, R
    Fang, XJ
    Ma, B
    Qiu, Y
    Lin, JH
    Pearson, PG
    Baillie, TA
    [J]. DRUG METABOLISM AND DISPOSITION, 2002, 30 (05) : 505 - 512
  • [7] Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A
    Shitara, Y
    Itoh, T
    Sato, H
    Li, AP
    Sugiyama, Y
    [J]. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 304 (02) : 610 - 616
  • [8] Atorvastatin transport in the Caco-2 cell model: Contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter
    Wu, XC
    Whitfield, LR
    Stewart, BH
    [J]. PHARMACEUTICAL RESEARCH, 2000, 17 (02) : 209 - 215