The Meyer-Schuster rearrangement of ethoxyalkynyl carbinols

被引：58

作者：

Lopez, Susana S. ^{[1
]}

Engel, Douglas A. ^{[1
]}

Dudley, Gregory B. ^{[1
]}

机构：

[1] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA

来源：

SYNLETT | 2007年 / 06期

关键词：

Meyer-Schuster; gold; alkoxyacetylene; propargyl alcohol; rearrangement;

D O I：

10.1055/s-2007-973885

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The combination of electron-rich alkoxyacetylenes and cationic gold catalysts provides excellent reactivity for the Meyer-Schuster rearrangement under mild conditions. Optimization of the reaction conditions with respect to stereoselectivity and investigations into the scope and mechanism of the rearrangement of secondary ethoxyalkynyl carbinols (gamma-ethoxy-substituted propargyl alcohols) to alpha,beta-unsaturated esters are described.

引用

页码：949 / 953

页数：5

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