Baker's asthma

被引:81
作者
Brant, Andrew [1 ]
机构
[1] Univ Otago, Wellington Hosp, Wellington, New Zealand
关键词
baker's asthma; flour; fungal alpha-amylase; wheat;
D O I
10.1097/ACI.0b013e328042ba77
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Purpose of review Baker's asthma is one of the leading causes of occupational asthma and this review describes recent developments in the field. Recent findings The location of bakery production has undergone change and, subsequently, so has the location of baker's asthma. Innovations in the baking industry have also led to new, potentially allergenic, ingredients. A new family of cereal allergens has been identified, including wheat thioredoxin hb (Tri a25). New enzymes are being added to bread that may have allergic potential. The relationship of specific sensitization and baker's asthma has been confirmed in further studies. Measuring specific sensitization to bakery allergens is an essential part of making the diagnosis but there is a lack of standardization of allergen tests. Advancements are being made in the measurement of airborne allergens through the Measurement of Occupational Allergen Exposure project and the development of novel measurement techniques. This will enable better exposure-response relationships and more accurate risk assessment. Summary Progress is being made to better identify bakery allergens and measure exposures accurately. Changes in the location of bread production and new allergens mean that the distribution and determinants of baker's asthma are changing.
引用
收藏
页码:152 / 155
页数:4
相关论文
共 25 条
[1]   Reported incidence of occupational asthma in France, 1996-99:: the ONAP programme [J].
Ameille, J ;
Pauli, G ;
Calastreng-Crinquand, A ;
Vervloët, D ;
Iwatsubo, Y ;
Popin, E ;
Bayeux-Dunglas, MC ;
Kopferschmitt-Kubler, MC ;
Arnaud, G ;
Bergeret, A ;
Blaumeiser, M ;
de Blay, F ;
Boitel, L ;
Bonnin, C ;
Brochard, P ;
Brun, J ;
Cabal, C ;
Cador, B ;
Caillaud, D ;
Cantineau, A ;
Chazenfus, J ;
Choudat, D ;
Conso, F ;
Costes, S ;
Couot, M ;
Curtes, JP ;
Dalphin, JC ;
Danaud, D ;
Danjou, P ;
Delemott, B ;
Deschamps, F ;
Dewitte, JD ;
Didier, A ;
Dhivert-Donnadieu, H ;
Doutrellot-Philippon, C ;
Dufresne-Benetti, F ;
Dumont, D ;
Dupas, D ;
Faucon, D ;
Fumery, JL ;
Gabrillargues, D ;
Garnier, R ;
Godard, P ;
Grudzien, F ;
Hémery, JM ;
Javelaud, B ;
Lasfargues, G ;
Leleu, B ;
Letourneux, M ;
Libert, B .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2003, 60 (02) :136-141
[2]   Airborne exposure to wheat allergens: measurement by human immunoglobulin G4 and rabbit immunoglobulin G immunoassays [J].
Bogdanovic, J. ;
Wouters, I. M. ;
Sander, I. ;
Raulf-Heimsoth, M. ;
Elms, J. ;
Rodrigo, M. J. ;
Heederik, D. J. J. ;
Doekes, G. .
CLINICAL AND EXPERIMENTAL ALLERGY, 2006, 36 (09) :1168-1175
[3]   Application of porous foams for size-selective measurements of airborne wheat allergen [J].
Bogdanovic, J ;
De Pater, AJ ;
Doekes, G ;
Wouters, IM ;
Heederik, DJJ .
ANNALS OF OCCUPATIONAL HYGIENE, 2006, 50 (02) :131-136
[4]   Supermarket baker's asthma: how accurate is routine health surveillance? [J].
Brant, A ;
Nightingale, S ;
Berriman, J ;
Sharp, C ;
Welch, J ;
Taylor, AJN ;
Cullinan, P .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2005, 62 (06) :395-399
[5]   The changing distribution of occupational asthma: a survey of supermarket bakery workers [J].
Brant, A ;
Berriman, J ;
Sharp, C ;
Welch, J ;
Zekveld, C ;
Nieuwenhuijsen, M ;
Elms, J ;
Newman-Taylor, A ;
Cullinan, P .
EUROPEAN RESPIRATORY JOURNAL, 2005, 25 (02) :303-308
[6]   Occupational asthma caused by cellulase and lipase in the detergent industry [J].
Brant, A ;
Hole, A ;
Cannon, J ;
Helm, J ;
Swales, C ;
Welch, J ;
Taylor, AN ;
Cullinan, P .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2004, 61 (09) :793-795
[7]   Sensitisation to occupational allergens in bakers' asthma and rhinitis:: a case-referent study [J].
Brisman, J ;
Lillienberg, L ;
Belin, L ;
Åhman, M ;
Järvholm, B .
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, 2003, 76 (02) :167-170
[8]   Exposure-response relations for self reported asthma and rhinitis in bakers [J].
Brisman, J ;
Järvholm, B ;
Lillienberg, L .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2000, 57 (05) :335-340
[9]   WORK-RELATED SYMPTOMS, SENSITIZATION, AND ESTIMATED EXPOSURE IN WORKERS NOT PREVIOUSLY EXPOSED TO FLOUR [J].
CULLINAN, P ;
LOWSON, D ;
NIEUWENHUIJSEN, MJ ;
SANDIFORD, C ;
TEE, RD ;
VENABLES, KM ;
MCDONALD, JC ;
TAYLOR, AJN .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1994, 51 (09) :579-583
[10]   Prospective study of work related respiratory symptoms in trainee bakers [J].
De Zotti, R ;
Bovenzi, M .
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 2000, 57 (01) :58-61