Disgust sensitivity predicts the insula and pallidal response to pictures of disgusting foods

被引:117
作者
Calder, Andrew J.
Beaver, John D.
Davis, Matt H.
van Ditzhuijzen, Jenneke
Keane, Jill
Lawrence, Andrew D.
机构
[1] MRC Cognit & Brain Sci Unit, Cambridge CB2 7EF, England
[2] Univ Amsterdam, Dept Expt Psychol, NL-1018 WB Amsterdam, Netherlands
基金
英国医学研究理事会;
关键词
appetite; basal ganglia; emotion; food rejection; reward;
D O I
10.1111/j.1460-9568.2007.05604.x
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The anterior insula has been implicated in coding disgust from facial, pictorial and olfactory cues, and in the experience of this emotion. Personality research has shown considerable variation in individuals' trait propensity to experience disgust ('disgust sensitivity'). Our study explored the neural expression of this trait, and demonstrates that individual variation in disgust sensitivity is significantly correlated with participants' ventroanterior insular response to viewing pictures of disgusting, but not appetizing or bland, foods. Similar correlations were also seen in the pallidum and orofacial regions of motor and somatosensory cortices. Our results also accord with comparative research showing an anterior to posterior gradient in the rat pallidum reflecting increased 'liking' of foods [Smith, K. S. and Berridge, K. C. (2005) J. Neurosci., 25, 849-8637].
引用
收藏
页码:3422 / 3428
页数:7
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