Biomimetic synthesis of calcium-strontium apatite hollow nanospheres

被引:7
作者
Gan Yong [1 ]
Han DongMei [1 ]
Gu FuBo [1 ]
Wang ZhiHua [1 ]
Guo GuangSheng [1 ]
机构
[1] Beijing Univ Chem Technol, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China
基金
中国国家自然科学基金;
关键词
calcium-strontium apatite; hollow nanosphere; biomimetic synthesis; BIOACTIVE BONE-CEMENT; HYDROXYAPATITE; FABRICATION; GELATIN; MECHANISMS; COLLAGEN;
D O I
10.1007/s11426-010-3171-4
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
In this work, calcium-strontium apatite (Sr-HA) hollow nanospheres were synthesized by a facile biomimetic method. The structure and property of Sr-HA were characterized by FESEM, TEM, HRTEM, XRD and FT-IR spectroscopy. The influences of different ratios of calcium and strontium on the morphologies of the Sr-HA products were investigated. The experimental results revealed that the hollow spherical Sr-HA, with a size of 30-120 nm in diameter, could be synthesized when the molar ratio of Ca/Sr was 1:1. The possible formation mechanism of the hollow Sr-HA was proposed. The drug release experiments indicated that the hollow spherical Sr-HA had the property of sustained release.
引用
收藏
页码:1723 / 1727
页数:5
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