Estimation of predictive accuracy in survival analysis using R and S-PLUS

被引:18
作者
Lusa, Lara [1 ]
Miceli, Rosalba
Mariani, Luigi
机构
[1] Fdn IRCCS Ist Nazl Tumori, Dept Expt Oncol, Milan, Italy
[2] Fdn Ist FIRC Oncol Mol, IFOM, Mol Canc Genet Grp, Milan, Italy
[3] Fdn IRCCS Ist Nazl Tumori, Unit Med Stat & Biometry, Milan, Italy
关键词
predictive accuracy; survival analysis; Cox model; parametric models; Bayesian model averaging; R; S-PLUS;
D O I
10.1016/j.cmpb.2007.05.009
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
When the purpose of a survival regression model is to predict future outcomes, the predictive accuracy of the model needs to be evaluated before practical application. Various measures of predictive accuracy have been proposed for survival data, none of which has been adopted as a standard, and their inclusion in statistical software is disregarded. We developed the SUREV library for R and S-PLUS, which includes functions for evaluating the predictive accuracy measures proposed by Schemper and Henderson. The library evaluates the predictive accuracy of parametric regression models and of Cox models. The predictive accuracy of the Cox model can be obtained also when time-dependent covariates are included because of non-proportional hazards or when using Bayesian model averaging. The use of the library is illustrated with examples based on a real data set. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:132 / 137
页数:6
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