The Wnt signaling pathway and bone metabolism

被引：190

作者：

Johnson, Mark L.

Kamel, Mohamed A.

机构：

[1] Univ Missouri, Sch Dent, Dept Oral Biol, Kansas City, MO 64108 USA

[2] Suez Canal Univ, Sch Med, Dept Rheumatol & Rehabil, Ismailia, Egypt

来源：

CURRENT OPINION IN RHEUMATOLOGY | 2007年 / 19卷 / 04期

关键词：

beta-catenin; arthritis; low-density lipoprotein receptor related protein 5; sclerostin; Wnt;

D O I：

10.1097/BOR.0b013e32816e06f9

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Understanding the role that the Writ signaling pathways play in the regulation of bone metabolism offers great promise for the developmental of new paradigms and pharmaceutical strategies for the treatment of various 1 diseases such as osteoporosis, rheumatoid arthritis and osteoarthritis. Progress in this regard has already been made.

引用

收藏

页码：376 / 382

页数：7

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