Chiral relay auxiliary for the synthesis of enantiomerically pure α-amino acids

被引：56

作者：

Bull, SD ^{[1
]}

Davies, SG ^{[1
]}

Epstein, SW ^{[1
]}

Ouzman, JVA ^{[1
]}

机构：

[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 06期

关键词：

D O I：

10.1039/a800407b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral auxiliary (3S)-N,N'-bis(p-methoxybenzyl)-3-iso-propylpiperazine-2,5-dione employs a chiral relay network based on non-stereogenic N-benzyl protecting groups to enhance diastereocontrol during enolate alkylation.

引用

页码：659 / 660

页数：2

共 14 条

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[9] Enantioselective synthesis of (R)- and (S)-alpha-amino acids using (6S)- and (6R)-6-methyl-morpholine-2,5-dione derivatives
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[J]. TETRAHEDRON-ASYMMETRY, 1996, 7 (01) : 189 - 196
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