Peroxisomes, lipid metabolism, and human disease

被引：26

作者：

Wanders, RJA ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Pediat, Emma Childrens Hosp, NL-1105 AZ Amsterdam, Netherlands

来源：

CELL BIOCHEMISTRY AND BIOPHYSICS | 2000年 / 32卷 / 1-3期

关键词：

peroxisomes; lipid metabolism; Zellweger syndrome; fatty acids; human disease; phospholipids; fatty acid oxidation;

D O I：

10.1385/CBB:32:1-3:89

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the past few years, much has been learned about the metabolic functions of peroxisomes. These studies have shown that peroxisomes play a major role in lipid metabolism, including fatty acid beta-oxidation, etherphospholipid biosynthesis, and phytanic acid alpha-oxidation. This article describes the current state of knowledge concerning the role of peroxisomes in these processes, especially in relation to various peroxisomal disorders in which there is an impairment in peroxisomal lipid metabolism.

引用

页码：89 / 106

页数：18

共 111 条

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