Ma'eganedin A, a new manzamine alkaloid from Amphimedon sponge

被引：24

作者：

Tsuda, M ^{[1
]}

Watanabe, D ^{[1
]}

Kobayashi, J ^{[1
]}

机构：

[1] Hokkaido Univ, Fac Pharmaceut Sci, Sapporo, Hokkaido 060, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(97)10842-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new manzamine-related tetrahydro-beta-carboline alkaloid with a methylene carbon bridge between N-2 and N-27, ma'eganedin A (1), has been isolated from an Okinawan marine sponge Amphimedon sp., and the structure including absolute stereochemistry was elucidated on the basis of spectroscopic data. The most stable conformation of 1 was deduced from molecular mechanics calculation. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1207 / 1210

页数：4

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