Cryopreservation and orthotopic transplantation of mouse ovaries: New approach in gamete banking

被引：123

作者：

Sztein, J ^{[1
]}

Sweet, H ^{[1
]}

Farley, J ^{[1
]}

Mobraaten, L ^{[1
]}

机构：

[1] Jackson Lab, Cryobiol Lab, Bar Harbor, ME 04609 USA

来源：

BIOLOGY OF REPRODUCTION | 1998年 / 58卷 / 04期

关键词：

D O I：

10.1095/biolreprod58.4.1071

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Mouse half ovaries were cryopreserved and orthotopically transplanted into ovariectomized recipients genetically identical to ovary donors except for the coat color gene. Fertility was reestablished in 57% of the female recipients, which became pregnant in an average of 40 days after transplantation of frozen-thawed half ovaries. These experiments demonstrate that ovary cryopreservation can be a very useful option for banking mouse germplasm, or managing subfertile animal colonies, when embryo or sperm freezing cannot be used or is not cost effective.

引用

页码：1071 / 1074

页数：4

共 16 条

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[2]

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[3]

Cox SL, 1996, J REPROD FERTIL, V107, P315, DOI 10.1530/jrf.0.1070315

[4]

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