Perspective of a new diagnostic for human trichomonosis

被引：3

作者：

Lecke, SB

Tasca, T

Souto, AA

De Carli, GA

机构：

[1] Pontificia Univ Catolica Rio Grande Sul, Fac Farm, Lab Parasitol Clin, BR-90619900 Porto Alegre, RS, Brazil

[2] Pontificia Univ Catolica Rio Grande Sul, Fac Quim, Lab Sintese Organ, BR-90619900 Porto Alegre, RS, Brazil

[3] Univ Fed Rio Grande Sul, Inst Ciencias Basicas Saude, Dept Bioquim, Porto Alegre, RS, Brazil

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2003年 / 98卷 / 02期

关键词：

Trichomonas vaginalis; diagnostic techniques; FLUTAX;

D O I：

10.1590/S0074-02762003000200018

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Several diagnostic techniques have been employed for the detection of Trichomonas vaginalis. Microtubules constitute the cytoskeleton in eukaryotic cells and are sensitive to antimitotic drugs, such as Taxol (paclitaxel). We used FLUTAX a fluorescent taxoid- to analyze the microtubule distribution in living trophozoites of T. vaginalis in urine and in vaginal discharge. A high intensity of fluorescence was observed in living T. vaginalis, epithelial cells and leukocytes present in urine and vaginal discharge. Our preliminary results show the perspective of a new diagnostic technique for trichomonosis and will contribute to the understanding of the cytoskeleton of T. vaginalis.

引用

页码：273 / 276

页数：4

共 25 条

[1] The fine structure of the axostyle and its associations with organelles in Trichomonads [J].