Epidemiology of autoimmune diseases in Denmark

被引：327

作者：

Eaton, William W.

Rose, Noel R.

Kalaydjian, Amanda

Pedersen, Marianne G.

Mortensen, Preben Bo

机构：

[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mental Hlth, Baltimore, MD 21205 USA

[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD 21205 USA

[3] Aarhus Univ, Natl Ctr Register Based Res, DK-8000 Aarhus C, Denmark

来源：

JOURNAL OF AUTOIMMUNITY | 2007年 / 29卷 / 01期

关键词：

prevalence; comorbidity; autoimmune diseases; population register; sex ratio; familial aggregation; MULTIPLE-SCLEROSIS; CELIAC-DISEASE; RHEUMATOID-ARTHRITIS; OLMSTED COUNTY; FAMILIAL RISK; PREVALENCE; DANISH; COPENHAGEN; DISORDERS; MINNESOTA;

D O I：

10.1016/j.jaut.2007.05.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co-morbidities in individuals among the 31 diseases, and familial aggregation among sibs, parents and offspring. The prevalence of any of the 31 diseases in the population is more than 5%. Within individuals, there is extensive comorbidity across the 31 diseases. Within families, aggregation is strongest for individual diseases and weak across diseases. These data confirm the importance of the autoimmune diseases as a group and suggest that common etiopathologies exist among them. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1 / 9

页数：9

共 48 条

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