Structures of the O-antigens of Proteus bacilli belonging to OX group (serogroups O1-O3) used in Weil-Felix test

被引：40

作者：

Ziolkowski, A

Shashkov, AS

Swierzko, AS

Senchenkova, SN

Toukach, FV

Cedzynski, M

Amano, KI

Kaca, W

Knirel, YA

机构：

[1] POLISH ACAD SCI, CTR MICROBIOL & VIROL, PL-90232 LODZ, POLAND

[2] ND ZELINSKII INST ORGAN CHEM, MOSCOW 117913, RUSSIA

[3] AKITA UNIV, SCH MED, CENT RES LAB, AKITA 010, JAPAN

来源：

FEBS LETTERS | 1997年 / 411卷 / 2-3期

基金：

俄罗斯基础研究基金会;

关键词：

O-antigen; lipopolysaccharide; bacterial polysaccharide structure; serological cross-reactivity; rickettsiosis; Weil-Felix test; Proteus; Rickettsia;

D O I：

10.1016/S0014-5793(97)00694-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Structures of the O-specific polysaccharide chains of lipopolysaccharides from Proteus group OX strains (serogroups O1-O3) used as antigens in Weil-Felix test for diagnosis of rickettsiosis, were established. From them, the acid-labile polysaccharide of Proteus vulgar is OX19 (O1) is built up of the following branched pentasaccharide repeating units connected via a phosphate group: [GRAPHICS] where QuiNAc stands for 2-acetamido-2,6-dideoxyglucose (N-acetylquinovosamine). The basis of serospecificity of the Proteus group OX antigens and their cross-reactivity with human anti-rickettsial antibodies is discussed. (C) 1997 Federation of European Biochemical Societies.

引用

页码：221 / 224

页数：4

共 29 条

[1] SEROLOGICAL REACTIVITY OF SERA FROM SCRUB TYPHUS PATIENTS AGAINST WEIL-FELIX TEST ANTIGENS [J].