Contribution of corticosteroid to the treatment of pain in the acute phase of Guillain-Barrd syndrome.

Introduction. Pain is a common problem in both adults and children with Guillain-Barre Syndrome (GBS). Corticosteroids are rarely used in the treatment of pain in the course of GBS, although some authors have pointed out their value for the treatment of neuropathic pain. We report four patients with GBS whose pain was rapidly relieved by administration of corticosteroids. Methods. We reviewed retrospectively a series of four patients with GBS seen from September 2001 to February 2003. All patients had plexual (Case 3), trunkular (case 1), radicular (case 2) or focal (case 4) pain. Pain was treated with corticosteroids via oral (cases I and 2) or intravenous routes (cases 3 and 4). Corticoids where used after failure of other analgesic agents. Results. Pain relief was obtained after the first administration and persisted even after tapering off steroid treatment No particular complication was observed during treatment course. Conclusion. Our experience suggests that controlled studies should be set up to evaluate the place of corticosteroid treatment for the management of pain in patients with GBS.