Cyclohexenyl nucleosides: Synthesis of cis-4-(9H-purin-9-yl)-2-cyclohexenylcarbinols.

被引：42

作者：

Konkel, MJ ^{[1
]}

Vince, R ^{[1
]}

机构：

[1] UNIV MINNESOTA,COLL PHARM,DEPT MED CHEM,MINNEAPOLIS,MN 55455

来源：

TETRAHEDRON | 1996年 / 52卷 / 03期

关键词：

D O I：

10.1016/0040-4020(95)00926-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Syntheses of the title compounds were accomplished in 6-7 steps, starting from cyclohexadiene and chlorosulphonyl isocyanate. The key step of the strategy involves a palladium coupling of cyclohexenyl dicarbonate 8 with either 6-chloropurine or 2-amino-6-chloropurine.

引用

页码：799 / 808

页数：10

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