Direct printing of bioceramic implants with spatially localized angiogenic factors

被引：99

作者：

Gbureck, Uwe

Hoelzel, Tanja

Doillon, Charles J.

Mueller, Frank A.

Barralet, Jake E.

机构：

[1] McGill Univ, Fac Dent, Montreal, PQ H3A 2B2, Canada

[2] Univ Laval, Dept Surg, Oncol & Mol Endocrinol Res Ctr, CHUL Res Ctr,CHUQ, Quebec City, PQ G1V 4G2, Canada

[3] Univ Wurzburg, Dept Funct Mat Med & Dent, D-97070 Wurzburg, Germany

[4] Univ Erlangen Nurnberg, Dept Mat Sci Biomat 3, D-91052 Erlangen, Germany

来源：

ADVANCED MATERIALS | 2007年 / 19卷 / 06期

关键词：

D O I：

10.1002/adma.200601370

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Direct printing of brushite and hydroxyapatite bioceramics at room temperature is used to construct model implants onto which the angiogenic compounds vascular endothelial growth factor (VEGF) and copper sulfate were adsorbed. This low-temperature direct approach offers several practical advantages and may find application in bone grafting. The figure shows examples of complex shapes made of brushite.

引用

页码：795 / +

页数：7

共 30 条

[1] Anterior cervical discectomy and fusion involving a polyetheretherketone spacer and bone morphogenetic protein [J].