The solvent influence on the positional selectivity of Novozym 435 during 1,3-diolein synthesis by esterification

被引：43

作者：

Duan, Zhang-Qun ^{[1
]}

Du, Wei ^{[1
]}

Liu, De-Hua ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem Engn, Beijing 100084, Peoples R China

来源：

BIORESOURCE TECHNOLOGY | 2010年 / 101卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Solvent influence; Positional selectivity; Novozym; 435; 1,3-Diolein; Esterification; ORGANIC-SOLVENTS; LIPASE; MEDIA; METHANOLYSIS; DEPENDENCE;

D O I：

10.1016/j.biortech.2009.11.087

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

The influence of solvents with a wide range of log P (from -0.23 to 4.5) on the positional selectivity of the immobilized lipase Novozym 435 during the esterification of oleic acid with glycerol for 1,3-diolein preparation was investigated. Analysis was performed on the basis of a simplified kinetic model of 1,3-diolein synthesis. The results showed that the preferential selectivity of Novozym 435 to 1-position over 2-position of the glycerol molecular became weaker and weaker with the increasing log P of the solvent. But after one 1-position was acylated, the preferential selectivity to the other 1-position over 2-position would be enhanced strongly for each solvent. The study also revealed that relatively hydrophilic solvent such as t-butanol was an ideal solvent for Novozym 435 catalyzed 1,3-diolein synthesis through esterification of oleic acid with glycerol. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2568 / 2571

页数：4

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