New possibility of application of bacteriophages to prevent infectious complications in free skin grafting (bacteriophages in skin grafting)

被引：2

作者：

Beschastnov, V. V. ^{[1
]}

Ryabkov, M. G. ^{[1
]}

Yudanova, T. N. ^{[2
]}

Pavlenko, I., V ^{[1
]}

Leont'ev, A. E. ^{[1
]}

Tulupov, A. A. ^{[1
]}

Kichin, V. V. ^{[1
]}

机构：

[1] City Clin Hosp 30, 85a,Berezovskaya Str, Nizhnii Novgorod 603157, Russia

[2] LLC Novye Perevyazochnye Mat, 2i Vil Zhuchki, Sergiyevo Posadsky Dist 141351, Moscow Oblast, Russia

来源：

BYULLETEN SIBIRSKOY MEDITSINY | 2021年 / 20卷 / 01期

关键词：

bacteriophages; free skin grafting; split thickness skin grafts; wound complications; microflora;

D O I：

10.20538/1682-0363-2021-1-16-22

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Aim. To prevent infectious processes in the area of a recipient wound in free skin grafting with a split-graft. Materials and methods. A method was developed for immobilizing bacteriophages in the area of split thickness skin grafts through transferring a solution containing bacteriophages into a gel form. Microbiological and clinical studies of the effectiveness of the proposed method were performed. Results. The viability of bacteriophages in a gel dressing for up to 4 days was confirmed, as well as the reduced likelihood of local infectious complications in skin grafting. Conclusion. The gel composition containing bacteriophages allows quick response to changes in current hospital microflora and effectively counteract the dangers of nosocomial infection.

引用

页码：16 / 22

页数：7