T cells: A proliferation of costimulatory molecules

被引:41
作者
Mueller, DL [1 ]
机构
[1] Univ Minnesota, Sch Med, Dept Med, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Sch Med, Ctr Immunol, Minneapolis, MN 55455 USA
关键词
D O I
10.1016/S0960-9822(00)00400-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The identification and characterization of a newly extended family of molecules related to the T-cell costimulatory proteins CD28 and B7 suggests that a distinct form of costimulatory signals could be important for effector T-cell responses outside of lymphoid tissues. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:R227 / R230
页数:4
相关论文
共 12 条
[1]   LICOS, a primordial costimulatory ligand? [J].
Brodie, D ;
Collins, AV ;
Iaboni, A ;
Fennelly, JA ;
Sparks, LM ;
Xu, XN ;
van der Merwe, PA ;
Davis, SJ .
CURRENT BIOLOGY, 2000, 10 (06) :333-336
[2]  
Dong HD, 1999, NAT MED, V5, P1365
[3]   Structure and evolution of the extended B7 family [J].
Henry, J ;
Miller, MM ;
Pontarotti, P .
IMMUNOLOGY TODAY, 1999, 20 (06) :285-288
[4]   ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28 [J].
Hutloff, A ;
Dittrich, AM ;
Beier, KC ;
Eljaschewitsch, B ;
Kraft, R ;
Anagnostopoulos, I ;
Kroczek, RA .
NATURE, 1999, 397 (6716) :263-266
[5]   CD28/B7 system of T cell costimulation [J].
Lenschow, DJ ;
Walunas, TL ;
Bluestone, JA .
ANNUAL REVIEW OF IMMUNOLOGY, 1996, 14 :233-258
[6]   The role of clonal anergy in the avoidance of autoimmunity: inactivation of autocrine growth without loss of effector function [J].
Malvey, EN ;
Telander, DG ;
Vanasek, TL ;
Mueller, DL .
IMMUNOLOGICAL REVIEWS, 1998, 165 :301-318
[7]   Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28 [J].
Metzler, WJ ;
Bajorath, J ;
Fenderson, W ;
Shaw, SY ;
Constantine, KL ;
Naemura, J ;
Leytze, G ;
Peach, RJ ;
Lavoie, TB ;
Mueller, L ;
Linsley, PS .
NATURE STRUCTURAL BIOLOGY, 1997, 4 (07) :527-531
[8]   CTLA-4 and T cell activation [J].
Oosterwegel, MA ;
Greenwald, RJ ;
Mandelbrot, DA ;
Lorsbach, RB ;
Sharpe, AH .
CURRENT OPINION IN IMMUNOLOGY, 1999, 11 (03) :294-300
[9]   BOTH EXTRACELLULAR IMMUNOGLOBIN-LIKE DOMAINS OF CD80 CONTAIN RESIDUES CRITICAL FOR BINDING T-CELL SURFACE-RECEPTORS CTLA-4 AND CD28 [J].
PEACH, RJ ;
BAJORATH, J ;
NAEMURA, J ;
LEYTZE, G ;
GREENE, J ;
ARUFFO, A ;
LINSLEY, PS .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (36) :21181-21187
[10]   B7h, a novel costimulatory homolog of b7.1 and b7.2, is induced by TNFα [J].
Swallow, MM ;
Wallin, JJ ;
Sha, WC .
IMMUNITY, 1999, 11 (04) :423-432