Autonomic dysfunctions in idiopathic Parkinson's disease

被引:70
作者
Jost, WH [1 ]
机构
[1] Deutsch Klin Diagnost, Fachbereich Neurol & Klin Neurophysiol, D-65191 Wiesbaden, Germany
关键词
Parkinson's disease; autonomic dysfunction;
D O I
10.1007/s00415-003-1105-z
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Most patients with Parkinson's disease experience autonomic dysfunction at some point in the course of their disease. In contrast to autonomic dysregulation in multisystem atrophy, they are less severe, and they frequently cause troublesome symptoms only in advanced stages of the disease. The quality of life is nevertheless substantially restricted. Cardiovascular, gastrointestinal and urogenital autonomic dysfunction is predominant. Appropriate diagnosis and treatment can greatly benefit the patient. An interdisciplinary approach is desirable in most cases.
引用
收藏
页码:28 / 30
页数:3
相关论文
共 11 条
[1]   The role of cardiac metaiodobenzylguanidine uptake in the differential diagnosis of parkinsonian syndromes [J].
Braune, S .
CLINICAL AUTONOMIC RESEARCH, 2001, 11 (06) :351-355
[2]  
EADIE MJ, 1965, AUSTRALAS ANN MED, V14, P13
[3]   GASTROINTESTINAL SYMPTOMS IN PARKINSON DISEASE - 18-MONTH FOLLOW-UP-STUDY [J].
EDWARDS, L ;
QUIGLEY, EMM ;
HOFMAN, R ;
PFEIFFER, RF .
MOVEMENT DISORDERS, 1993, 8 (01) :83-86
[4]   Orthostatic hypotension from sympathetic denervation in Parkinson's disease [J].
Goldstein, DS ;
Holmes, CS ;
Dendi, R ;
Bruce, SR ;
Li, ST .
NEUROLOGY, 2002, 58 (08) :1247-1255
[5]   The effect of catechol-O-methyltransferase inhibition with entacapone on cardiovascular autonomic responses in L-dopa-treated patients with Parkinson's disease [J].
Lyytinen, J ;
Sovijärvi, A ;
Kaakkola, S ;
Gordin, A ;
Teräväinen, H .
CLINICAL NEUROPHARMACOLOGY, 2001, 24 (01) :50-57
[6]  
Martignoni E, 1995, J NEURAL TRANSM-SUPP, P11
[7]  
Mesec A, 1993, Clin Auton Res, V3, P339, DOI 10.1007/BF01827336
[8]   POSTPRANDIAL AND ORTHOSTATIC HYPOTENSION IN PARKINSONS-DISEASE [J].
MICIELI, G ;
MARTIGNONI, E ;
CAVALLINI, A ;
SANDRINI, G ;
NAPPI, G .
NEUROLOGY, 1987, 37 (03) :386-393
[9]   CARDIOVASCULAR REFLEXES IN PARKINSONS-DISEASE [J].
TURKKA, JT ;
TOLONEN, U ;
MYLLYLA, VV .
EUROPEAN NEUROLOGY, 1987, 26 (02) :104-112
[10]  
Zesiewicz TA, 2000, MOVEMENT DISORD, V15, P305, DOI 10.1002/1531-8257(200003)15:2<305::AID-MDS1015>3.0.CO