Blastocystis in humans and animals:: new insights using modern methodologies

被引:134
作者
Tan, KSW [1 ]
机构
[1] Natl Univ Singapore, Fac Med, Dept Microbiol, Lab Mol & Cellular Parasitol, S-117597 Singapore, Singapore
关键词
Blastocystis; taxonomy; morphology; zoonosis; ultrastructure; molecular biology;
D O I
10.1016/j.vetpar.2004.09.017
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Among the waterborne protozoan parasites of medical and veterinary importance, Blastocystis is perhaps one of the less well-understood. However, in recent years, there has been a surge of interest in the organism, fueled in part by the possible association of Blastocystis infection with intestinal disorders, and its unusual taxonomic affiliations. Although there is information on the parasite's morphology, taxonomy and mode of transmission, its pathogenicity, life cycle, and function of certain organelles continue to baffle investigators. The clinical relevance of Blastocystis will be better answered once an animal model is found. Blastocystis infections have a worldwide distribution but prevalence is highest in areas with poor hygiene and deficient sanitation services and facilities. Application of modern molecular tools has advanced knowledge of the organism's genetic diversity, taxonomy and zoonotic potential. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:121 / 144
页数:24
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