Neuropeptide Y and epilepsy: recent progress, prospects and controversies

被引：51

作者：

Baraban, SC ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol Surg, Epilepsy Res Lab, San Francisco, CA 94143 USA

来源：

NEUROPEPTIDES | 2004年 / 38卷 / 04期

关键词：

hippocampus; interneuron; mice; pharmacology; seizure;

D O I：

10.1016/j.npep.2004.04.006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neuropeptide Y (NPY), a 36 amino-acid member of the pancreatic polypeptide family, has received considerable attention in recent years as an endogenous modulator of epileptic activity. Prominently expressed in brain regions involved in seizure generation and propagation, NPY can exert powerful effects on synaptic transmission. Here, we discuss the anti-epileptic actions of NPY and receptor subtypes responsible. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：261 / 265

页数：5

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