Endocytosis: Why not wait to deubiquitinate?

被引：10

作者：

Carthew, RW ^{[1
]}

Xu, CY ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Sci Biol, Pittsburgh, PA 15260 USA

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 14期

关键词：

D O I：

10.1016/S0960-9822(00)00587-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Deubiquitination by the Fat facets protein - a regulator of photoreceptor differentiation during Drosophila eye development - has been found to activate endocytosis, while ubiquitination inhibits endocytosis, Surprisingly, this is the opposite effect that ubiquitination has on endocytosis of many plasma membrane proteins.

引用

页码：R532 / R534

页数：3

共 17 条

[1] BEJSOVEC A, 1995, GENETICS, V139, P309
[2] Cadavid ALM, 2000, DEVELOPMENT, V127, P1727
[3] FISCHERVIZE JA, 1992, DEVELOPMENT, V116, P985
[4] Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis
Hicke, L
Riezman, H
[J]. CELL, 1996, 84 (02) : 277 - 287
[5] Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins
Hicke, L
[J]. FASEB JOURNAL, 1997, 11 (14) : 1215 - 1226
[6] Huang YZ, 1996, DEVELOPMENT, V122, P3207
[7] CONTROL OF CELL FATE BY A DEUBIQUITINATING ENZYME ENCODED BY THE FAT FACETS GENE
HUANG, YZ
BAKER, RT
FISCHERVIZE, JA
[J]. SCIENCE, 1995, 270 (5243) : 1828 - 1831
[8] Epsin 1 undergoes nucleocytosolic shuttling and its Eps15 interactor NH2-terminal homology (ENTH) domain, structurally similar to armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn2+ finger protein (PLZF)
Hyman, J
Chen, H
Di Fiore, PP
De Camilli, P
Brunger, AT
[J]. JOURNAL OF CELL BIOLOGY, 2000, 149 (03) : 537 - 546
[9] Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome
Lam, YA
Xu, W
DeMartino, GN
Cohen, RE
[J]. NATURE, 1997, 385 (6618) : 737 - 740
[10] Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
Levkowitz, G
Waterman, H
Ettenberg, SA
Katz, M
Tsygankov, AY
Alroy, I
Lavi, S
Iwai, K
Reiss, Y
Ciechanover, A
Lipkowitz, S
Yarden, Y
[J]. MOLECULAR CELL, 1999, 4 (06) : 1029 - 1040

← 1 2 →