Thalidomide for severe systemic onset juvenile rheumatoid arthritis: A multicenter study

被引：63

作者：

Lehman, TJA

Schechter, S

Sundel, RP

Oliveira, SK

Huttenlocher, A

Onel, KB

机构：

[1] Hosp Special Surg, Div Pediat Rheumatol, New York, NY 10021 USA

[2] Cornell Univ, Dept Pediat, Sanford Weill Med Coll, New York, NY USA

[3] Childrens Hosp, Med Ctr, Div Immunol, Boston, MA 02115 USA

[4] Fed Univ Rio De Janeiro, Rio De Janeiro, Brazil

[5] Univ Wisconsin, Sch Med, Dept Pediat, Madison, WI USA

来源：

JOURNAL OF PEDIATRICS | 2004年 / 145卷 / 06期

关键词：

D O I：

10.1016/j.jpeds.2004.08.020

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Thirteen children with difficult systemic onset juvenile rheumatoid arthritis were treated with thalidomide. At 6 months, 11 of the 13 were able to reduce their use of prednisone (P <.002), with a concurrent improvement in erythrocyte sedimentation rate (P <.0001) and an increase in hemoglobin level (P < 0.005). Juvenile rheumatoid arthritis improvement scores greater than or equal to50% were obtained by 10 of the 13 children.

引用

页码：856 / 857

页数：2

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