Arabidopsis NPH1: A protein kinase with a putative redox-sensing domain

被引：584

作者：

Huala, E ^{[1
]}

Oeller, PW ^{[1
]}

Liscum, E ^{[1
]}

Han, IS ^{[1
]}

Larsen, E ^{[1
]}

Briggs, WR ^{[1
]}

机构：

[1] CARNEGIE INST WASHINGTON, DEPT PLANT BIOL, STANFORD, CA 94305 USA

来源：

SCIENCE | 1997年 / 278卷 / 5346期

关键词：

D O I：

10.1126/science.278.5346.2120

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The NPH1 (nonphototropic hypocotyl 1) gene encodes an essential component acting very early in the signal-transduction chain for phototropism. Arabidopsis NPH? contains a serine-threonine kinase domain and LOV1 and LOV2 repeats that share similarity (36 to 56 percent) with Halobacterium salinarium Bat, Azotobacter vinelandii NIFL, Neurospora crassa White Collar-1, Escherichia call Aer, and the fag family of potassium-channel proteins from Drosophila and mammals. Sequence similarity with a known (NIFL) and a suspected (Aer) flavoprotein suggests that NPH1 LOV1 and LOV2 may be flavin-binding domains that regulate kinase activity in response to blue light-induced redox changes.

引用

页码：2120 / 2123

页数：4

共 45 条

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