An Escherichia coli reference collection group B2-and uropathogen-associated polymorphism in the rpoS-mutS region of the E-coli chromosome

被引:26
作者
Culham, DE [1 ]
Wood, JM [1 ]
机构
[1] Univ Guelph, Dept Microbiol, Guelph, ON N1G 2W1, Canada
关键词
D O I
10.1128/JB.182.21.6272-6276.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Chromosomal DNAs of enterohemorrhagic, uropathogenic, and laboratory attenuated Escherichia coli strains differ in the rpoS-mutS region. Many uropathogens lack a deletion and an insertion characteristic of enterohemorrhagic strains. At the same chromosomal position, they harbor a 2.1-kb insertion of unknown origin with a base composition suggestive of horizontal gene transfer. Unlike virulence determinants associated with urinary tract infection and/or neonatal meningitis (pap or prs, sfa, kps, and hly), the 2.1-kb insertion is shared by all group B2 strains of the E. coli Reference Collection.
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页码:6272 / 6276
页数:5
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