A mild, efficient and selective deprotection of t-butyldimethylsilyl-protected phenols using cesium carbonate

被引：38

作者：

Jiang, ZY ^{[1
]}

Wang, YG ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 19期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0040-4039(03)00736-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mild and efficient method for the deprotection of aryl t-butyldimethysilyl (TBS) ethers is described. The protecting group TBS could be cleaved from aryl silyl ethers using cesium carbonate in DMF-H2O at room temperature to give the corresponding phenols in excellent yields. The reaction conditions allowed selective deprotection of aryl TBS-protected phenols in the presence of TBS, pbenyloxycarbonyl or tetrahydropyranyl-protected alcohols. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：3859 / 3861

页数：3

共 19 条

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