Biochemical IC chip toward cell free DNA protein synthesis

被引：31

作者：

Ikuta, K ^{[1
]}

Maruo, S ^{[1
]}

Fukaya, Y ^{[1
]}

Fujisawa, T ^{[1
]}

机构：

[1] Nagoya Univ, Sch Engn, Dept Micro Syst Engn, Chikusa Ku, Nagoya, Aichi 46401, Japan

来源：

MICRO ELECTRO MECHANICAL SYSTEMS - IEEE ELEVENTH ANNUAL INTERNATIONAL WORKSHOP PROCEEDINGS | 1998年

关键词：

D O I：

10.1109/MEMSYS.1998.659742

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

The several type of biochemical IC chips with photo detective micro reactor has been developed. The real time monitoring and controlling cell free synthesis of protein was demonstrated successfully. The photo protein of firefly so called Luciferase was synthesized. The biochemical luminescence was monitored by built-in photo diode in the micro reactor to transfer reaction status into voltage signal. Feedback control synthetic reaction was verified experimentally. The results achieved here should be key technology for future DNA and RNA synthesis without biological cell.

引用

页码：131 / 136

页数：4