Alteration of mean wall shear stress near an oscillating stagnation point

被引:15
作者
Hazel, AL [1 ]
Pedley, TJ [1 ]
机构
[1] Univ Cambridge, Dept Appl Math & Theoret Phys, Cambridge CB3 9EW, England
来源
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 1998年 / 120卷 / 02期
基金
英国惠康基金;
关键词
D O I
10.1115/1.2798306
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The size opposite an end-to-side anastomosis, resulting from femoral bypass surgery, and the carotid sinus are two regions well known to be prone to fibrous intimal hyperplasia or atherogenesis, respectively. The blood flow at these two sites features a stagnation point, which oscillates in strength and position. Mathematical models are used to determine some of the features of such a flow; in particular, the mean wall shear stress is calculated. The positional oscillations cause a significant change in the distribution and magnitude of the mean wall shear stress from that of the well-studied case of a stagnation point that oscillates only in strength. It is therefore proposed that the recorded effect of time dependence in the flow upon atherogenesis could still be a result of the distribution of the mean and not the time-varying components of the wall shear stress.
引用
收藏
页码:227 / 237
页数:11
相关论文
共 26 条
[1]   ANASTOMOTIC INTIMAL HYPERPLASIA - MECHANICAL INJURY OR FLOW INDUCED [J].
BASSIOUNY, HS ;
WHITE, S ;
GLAGOV, S ;
CHOI, E ;
GIDDENS, DP ;
ZARINS, CK .
JOURNAL OF VASCULAR SURGERY, 1992, 15 (04) :708-717
[2]   STEADY FLOW IN A MODEL OF THE HUMAN CAROTID BIFURCATION .1. FLOW VISUALIZATION [J].
BHARADVAJ, BK ;
MABON, RF ;
GIDDENS, DP .
JOURNAL OF BIOMECHANICS, 1982, 15 (05) :349-362
[3]   Influence of non-Newtonian behavior of blood on flow in an elastic artery model [J].
Dutta, A ;
Tarbell, JM .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1996, 118 (01) :111-119
[4]   ARTERIOSCLEROSIS RESEARCH USING VASCULAR FLOW MODELS - FROM 2-D BRANCHES TO COMPLIANT REPLICAS [J].
FRIEDMAN, MH .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1993, 115 (04) :595-601
[5]   THE ROLE OF FLUID-MECHANICS IN THE LOCALIZATION AND DETECTION OF ATHEROSCLEROSIS [J].
GIDDENS, DP ;
ZARINS, CK ;
GLAGOV, S .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1993, 115 (04) :588-594
[6]   THE LAMINAR BOUNDARY LAYER ON OSCILLATING PLATES AND CYLINDERS [J].
GLAUERT, MB .
JOURNAL OF FLUID MECHANICS, 1956, 1 (01) :97-110
[7]  
HENRY FS, 1994, BIOFLUID MECH, P497
[8]  
Hiemenz K., 1911, DINGLERS POLYTECHNIS, V326, P321
[9]   FEMORAL ARTERY FLOW, LIMB BLOOD VOLUME AND CARDIAC OUTPUT THROUGH CONTINUOUSLY RECORDED INDICATOR-DILUTION CURVES [J].
HOBBS, JT ;
EDWARDS, EA .
ANNALS OF SURGERY, 1963, 158 (02) :159-&
[10]   Numerical study of wall mechanics and fluid dynamics in end-to-side anastomoses and correlation to intimal hyperplasia [J].
Hofer, M ;
Rappitsch, G ;
Perktold, K ;
Trubel, W ;
Schima, H .
JOURNAL OF BIOMECHANICS, 1996, 29 (10) :1297-1308