The induction of apoptosis by local anesthetics: A comparison between lidocaine and ropivacaine

被引:53
作者
Boselli, E
Duflo, F
Debon, R
Allaouchiche, B
Chassard, D [1 ]
Thomas, L
Portoukalian, J
机构
[1] Hop Hotel Dieu, Serv Anesthesie Reanimat, Dept Anesthesiol & Intens Care, F-69002 Lyon, France
[2] Ctr Hosp Lyon Sud, INSERM, Unite 346, Lab Glycobiol, F-69310 Pierre Benite, France
关键词
D O I
10.1213/01.ANE.0000047201.85815.9D
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
This study suggests that lidocaine can induce apoptosis (detected by dual staining with Annexin V and propidium iodide) on T-cell line cultures in a time-dependent manner. This was not observed with ropivacaine.
引用
收藏
页码:755 / 756
页数:2
相关论文
共 9 条
  • [1] Does chronic occupational exposure to volatile anesthetic agents influence the rate of neutrophil apoptosis?
    Goto, Y
    Gallagher, J
    Fanning, N
    Wang, JH
    McCusker, S
    Redmond, P
    Shorten, G
    [J]. CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 2000, 47 (04): : 350 - 353
  • [2] Potential neurotoxicity of spinal anesthesia with lidocaine
    Johnson, ME
    [J]. MAYO CLINIC PROCEEDINGS, 2000, 75 (09) : 921 - 932
  • [3] JOHNSON ME, 2001, ANESTHESIOLOGY S, V95, pA985
  • [4] NASSOGNE MC, 1998, ANN NY ACAD SCI, V846, P54
  • [5] Comparison of the effects of bupivacaine and ropivacaine on heart cell mitochondrial bioenergetics
    Sztark, F
    Malgat, M
    Dabadie, P
    Mazat, JP
    [J]. ANESTHESIOLOGY, 1998, 88 (05) : 1340 - 1349
  • [6] Effects of chronic occupational exposure to anaesthetic gases on the rate of neutrophil apoptosis among anaesthetists
    Tyther, R
    Halligan, M
    Wang, J
    Redmond, HP
    Shorten, G
    [J]. EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2002, 19 (08) : 604 - 608
  • [7] The effect of the anaesthetic agent isoflurane on the rate of neutrophil apoptosis in vitro
    Tyther, R
    Fanning, N
    Halligan, M
    Wang, J
    Redmond, HP
    Shorten, G
    [J]. IRISH JOURNAL OF MEDICAL SCIENCE, 2001, 170 (01) : 41 - 44
  • [8] A NOVEL ASSAY FOR APOPTOSIS - FLOW CYTOMETRIC DETECTION OF PHOSPHATIDYLSERINE EXPRESSION ON EARLY APOPTOTIC CELLS USING FLUORESCEIN-LABELED ANNEXIN-V
    VERMES, I
    HAANEN, C
    STEFFENSNAKKEN, H
    REUTELINGSPERGER, C
    [J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1995, 184 (01) : 39 - 51
  • [9] Weinberg G, 1998, ANESTHESIOLOGY, V89, pU1065